Kanamycin

Chemical Structure / Formula of Kanamycin

  • Formula: C18H36N4O11
  • Similar to neomycin but slightly less toxic.

Kanamycin

Mechanism of Action

  • Inhibits 30S ribosomal subunit, leading to bacterial cell death.

Uses of Kanamycin

  • Used in tuberculosis (as a second-line drug).
  • Treats severe Gram-negative infections when other antibiotics fail.
  • Topical use for eye and ear infections.

Side Effects

  • Ototoxicity and nephrotoxicity (dose-dependent).
  • Neuromuscular blockade (rare but serious).

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