Lamivudine (3TC)

Chemical Structure / Formula of Lamivudine (3TC)

  • Formula: C₈H₁₁N₃O₃S
  • Structure: Cytosine analog with a sulfur (-S) group.

Lamivudine (3TC)

Mechanism of Action

  • Converted to Lamivudine triphosphate, which inhibits HIV reverse transcriptase.
  • Also inhibits HBV polymerase (used in hepatitis B treatment).

Uses of Lamivudine (3TC)

  • HIV/AIDS therapy (HAART regimen, commonly used with Abacavir or Zidovudine).
  • Chronic hepatitis B (HBV therapy).

Side Effects

  • Well tolerated (mild GI upset, headache, fatigue).
  • Rare: pancreatitis, lactic acidosis.

Click Here to Watch the Best Pharma Videos

Leave a Comment

This site uses Akismet to reduce spam. Learn how your comment data is processed.