Mefloquine

Chemical Structure / Formula of Mefloquine

  • Formula: C₁₇H₁₆F₆N₂O
  • Structure: A quinoline derivative with fluorinated groups.

Mefloquine

Mechanism of Action

  • Disrupts heme metabolism and damages the parasite’s food vacuole.

Uses of Mefloquine

  • Prophylaxis and treatment of chloroquine-resistant malaria.

Side Effects

  • Neuropsychiatric symptoms (nightmares, anxiety, hallucinations).
  • QT prolongation, GI distress.

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