Naftifine Hydrochloride

Chemical Structure / Formula of Naftifine Hydrochloride

  • Formula: C₂₁H₂₁N · HCl
  • Structure: Allylamine antifungal with a naphthalene core.

Naftifine Hydrochloride

Mechanism of Action

  • Inhibits squalene epoxidase, blocking ergosterol synthesis and leading to toxic squalene accumulation.

Uses of Naftifine Hydrochloride

  • Topical antifungal (tinea infections, athlete’s foot, jock itch, ringworm).

Side Effects

  • Skin irritation, redness, burning.

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