Ritonavir

Chemical Structure / Formula of Ritonavir

  • Formula: C₃₇H₄₈N₆O₅S₂
  • Structure: Peptidomimetic protease inhibitor with a thiazole ring.

Ritonavir

Mechanism of Action

  • Inhibits HIV protease, preventing viral replication.
  • Strong CYP3A4 inhibitor (boosts levels of other protease inhibitors).

Uses of Ritonavir

  • HIV/AIDS therapy (mainly used as a booster for other PIs like Lopinavir).

Side Effects

  • GI upset, hepatotoxicity.
  • Hyperlipidemia, insulin resistance.

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