Thiabendazole

Chemical Structure / Formula of Thiabendazole

  • Formula: C₁₀H₇N₃S
  • Structure: A benzimidazole derivative with a thiazole ring.

Thiabendazole

Mechanism of Action

  • Inhibits microtubule synthesis, disrupting worm metabolism and reproduction.
  • Inhibits mitochondrial fumarate reductase, affecting parasite energy production.

Uses of Thiabendazole

  • Strongyloidiasis, cutaneous larva migrans, Trichinosis.

Side Effects

  • GI upset, dizziness, hepatotoxicity.
  • Hypersensitivity reactions (Stevens-Johnson syndrome).

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