Classification of Anti-Tubercular Agents

Classification of Anti-Tubercular Agents explains grouping of TB drugs into first-line and second-line agents based on efficacy and use.

Classification of Anti-Tubercular Agents

• Anti-tubercular agents are used to treat infections caused by Mycobacterium tuberculosis and can be classified based on their mechanism of action and chemical structure.
• They are often categorized into first-line and second-line drugs, and further grouped into two main types:

1. Synthetic Anti-Tubercular Agents

• These are chemically synthesized drugs that target various biochemical pathways in tuberculosis.
• Examples:
  1. Isoniazid
  2. Ethionamide
  3. Ethambutol
  4. Pyrazinamide
  5. Para-aminosalicylic acid

2. Anti-Tubercular Antibiotics

• These agents are naturally derived or semi-synthetic and work by inhibiting mycobacterial growth through mechanisms such as interfering with bacterial RNA synthesis, protein synthesis, or cell wall formation.
• Examples:
  1. Rifampicin
  2. Rifabutin
  3. Cycloserine
  4. Streptomycin
  5. Capreomycin sulphate

Click Here to Watch the Best Pharma Videos